Divergent skeletal muscle respiratory capacities in rats artificially selected for high and low running ability: a role for Nor1?
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چکیده
منابع مشابه
Divergent skeletal muscle respiratory capacities in rats artificially selected for high and low running ability: a role for Nor1?
Inactivity-related diseases are becoming a huge burden on Western society. While there is a major environmental contribution to metabolic health, the intrinsic properties that predispose or protect against particular health traits are harder to define. We used rat models of inborn high running capacity (HCR) and low running capacity (LCR) to determine inherent differences in mitochondrial volum...
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Enhanced cardiac protein glycosylation (O-GlcNAc) of selected mitochondrial proteins in rats artificially selected for low running capacity.
O-linked β-N-acetyl glucosamine (O-GlcNAc) is a posttranslational modification consisting of a single N-acetylglucosamine moiety attached by an O-β-glycosidic linkage to serine and threonine residues of both nuclear and cytosolic proteins. Analogous to phosphorylation, the modification is reversible and dynamic, changing in response to stress, nutrients, hormones, and exercise. Aims of this stu...
متن کاملSelected contribution: skeletal muscle capillarity and enzyme activity in rats selectively bred for running endurance.
To attempt to explain the difference in intrinsic (untrained) endurance running capacity in rats selectively bred over seven generations for either low (LCR) or high running capacity (HCR), the relationship among skeletal muscle capillarity, fiber composition, enzyme activity, and O(2) transport was studied. Ten females from each group [body wt: 228 g (HCR), 247 g (LCR); P = 0.03] were studied ...
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ژورنال
عنوان ژورنال: Journal of Applied Physiology
سال: 2012
ISSN: 8750-7587,1522-1601
DOI: 10.1152/japplphysiol.00788.2012